The Gainesville campus of NCTC is its main campus, serving as home to the central administration and governing board. The main campus serves all of Cooke County, of which Gainesville, Texas is the county seat and largest city. In its present location since 1960, the college district was created as a separate entity from the local public school district. Both the Gainesville and Corinth campuses are situated along the "Interstate 35 Corridor" that extends from the Dallas-Fort Worth Metroplex northward through Lewisville, Denton and points north along the route to Oklahoma City.